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Marijuana, Anxiety, Depression, and Mental Health

  • Writer: Lorrie Smith-Esterle
    Lorrie Smith-Esterle
  • Oct 10, 2025
  • 3 min read

Updated: Nov 25, 2025


As a mental health provider, I’m often asked whether marijuana (cannabis) can help with anxiety or depression. I completely understand why people are curious. When you’re hurting, the idea of something that might bring quick relief can be very appealing. And yes—some people do notice that they feel calmer or more relaxed for a short while after using marijuana.


But based on both research and what I’ve seen in my own practice, marijuana usually doesn’t help in the long run. In fact, for many people it makes anxiety and depression worse over time. It can also increase the risk of more serious concerns, including psychosis.


Anxiety and Mood

Marijuana doesn’t treat the underlying causes of anxiety or depression. While it may take the edge off for a little while, I’ve seen symptoms worsen in patients who use it regularly.


Energy and Motivation

Many of my patients tell me that regular marijuana use leaves them feeling more sluggish and unmotivated. Unfortunately, that lack of energy can make depression harder to manage.


Suicidal Thoughts

What concerns me most is the research linking marijuana use with suicidal thoughts, especially among teens and young adults.


If you or someone you love is struggling with thoughts of suicide, please know that help is available:

  • In the U.S., you can dial 988 anytime to reach the Suicide & Crisis Lifeline and speak to someone right away.

  • If you are a patient of Kentucky Psychiatric Care, PLLC and are in crisis, please call our office at (502) 830-9330 during business hours.

  • If you are in immediate danger, please call 911 or go to the nearest emergency room.


You are not alone, and support is available.


The Risk of Psychosis

Psychosis means losing touch with reality—experiencing hallucinations or delusions. Studies show that frequent or high-potency marijuana use can raise this risk. The risk is even greater if someone has a family history of conditions like bipolar disorder and schizophrenia.


Fertility and Reproductive Health

Emerging research suggests that marijuana may also impact fertility in both men and women. Studies have linked regular cannabis use to lower sperm count and motility in men, and to possible ovulatory changes in women. While more research is needed, these findings add to growing evidence that marijuana can influence hormone balance and reproductive health.


Why These Risks Happen

Here’s what we know about why marijuana can have these effects:

  • High THC levels: Today’s cannabis products are much stronger than in the past. High THC levels can trigger anxiety, paranoia, and confusion.

  • Dependence and withdrawal: Regular use can lead to dependence. When people stop suddenly, I often hear about irritability, restlessness, and trouble sleeping.

  • Sleep disruption: Even though marijuana might help some people fall asleep faster, it disrupts deep, restorative sleep. And poor sleep almost always makes anxiety and depression worse.


What I Encourage My Patients to Remember

  • Marijuana is not a proven treatment for anxiety or depression.

  • Regular use often makes symptoms worse over time.

  • There are safer and more effective options—like therapy, lifestyle strategies, and medications—that can provide real, lasting relief.


Bottom Line

If you’re living with anxiety or depression, it’s natural to wonder if marijuana might help. While some people do feel short-term relief, the long-term effects are often harmful, both to mood and overall mental health.


The good news is that there are safe, effective treatments available—and you don’t have to figure this out alone. If you’re struggling, I encourage you to reach out. Together, we can explore options that truly support your mental health and well-being.


Written by Lorrie Smith-Esterle, DNP, PMHNP-BC

Kentucky Psychiatric Care, PLLC


References

Research continues to evolve on the effects of marijuana on mental and physical health. The following sources informed the information shared in this post:


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